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Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility.
Ferguson, Jalisa H; De Los Santos, Zeus; Devi, Saroja N; Kaluz, Stefan; Van Meir, Erwin G; Zingales, Sarah K; Wang, Binghe.
Afiliação
  • Ferguson JH; a Department of Chemistry , Georgia State University , Atlanta , GA , USA.
  • De Los Santos Z; a Department of Chemistry , Georgia State University , Atlanta , GA , USA.
  • Devi SN; b Departments of Neurosurgery and Hematology and Medical Oncology, School of Medicine and Winship Cancer Institute , Emory University , Atlanta , GA , USA.
  • Kaluz S; b Departments of Neurosurgery and Hematology and Medical Oncology, School of Medicine and Winship Cancer Institute , Emory University , Atlanta , GA , USA.
  • Van Meir EG; b Departments of Neurosurgery and Hematology and Medical Oncology, School of Medicine and Winship Cancer Institute , Emory University , Atlanta , GA , USA.
  • Zingales SK; a Department of Chemistry , Georgia State University , Atlanta , GA , USA.
  • Wang B; c Department of Chemistry and Physics , Armstrong State University , Savannah , GA , USA.
J Enzyme Inhib Med Chem ; 32(1): 992-1001, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28766956

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzopiranos / Desenho de Fármacos / Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzopiranos / Desenho de Fármacos / Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article