A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-&#954;B activation.

Osako, Miho; Itsumi, Momoe; Yamaguchi, Haruka; Takeuchi, Hiroaki; Yamaoka, Shoji

A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-κB activation.

Osako, Miho; Itsumi, Momoe; Yamaguchi, Haruka; Takeuchi, Hiroaki; Yamaoka, Shoji.

Afiliação

Osako M; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Itsumi M; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Yamaguchi H; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Takeuchi H; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Yamaoka S; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

J Cell Biochem ; 119(2): 1475-1487, 2018 02.

Article em En | MEDLINE | ID: mdl-28771803

Assuntos

Núcleo Celular/metabolismo; NF-kappa B/genética; Ésteres de Forbol/farmacologia; Células THP-1/citologia; Proteína 3 Induzida por Fator de Necrose Tumoral alfa/genética; Apoptose; Diferenciação Celular/efeitos dos fármacos; Sobrevivência Celular; Humanos; Mutação; Inibidor de NF-kappaB alfa/genética; Inibidor de NF-kappaB alfa/metabolismo; NF-kappa B/metabolismo; Domínios Proteicos; Células THP-1/efeitos dos fármacos; Células THP-1/metabolismo; Proteína 3 Induzida por Fator de Necrose Tumoral alfa/química; Proteína 3 Induzida por Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

A20; NF-κB; cell differentiation; cell survival; macrophage; monocyte

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ésteres de Forbol / Núcleo Celular / NF-kappa B / Proteína 3 Induzida por Fator de Necrose Tumoral alfa / Células THP-1 Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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