Effects of acute physical exercise in the light phase of sleep in rats with temporal lobe epilepsy.
Epilepsy Res
; 136: 54-61, 2017 10.
Article
em En
| MEDLINE
| ID: mdl-28772197
ABSTRACT
OBJECTIVE:
Our aim was to investigate the influence of an acute exercise session on sleep pattern in rats with temporal lobe epilepsy (TLE).METHODS:
Twenty male Wistar rats were randomly assigned to 4 groups control (C); acute exercise (EX); epilepsy (E) and epilepsy acute exercise (EEX). Two sleep electrocorticography recordings were performed during the light phase [baseline and day 2 (after the acute physical exercise session)]. After baseline recording, the exercise groups (EX and EEX) were submitted to an exercise session on a motor-driven treadmill at 12m/min for 30min. Twelve hours later, the rats were submitted to the second sleep recording.RESULTS:
At baseline, the E group showed a higher wakefulness and a lower Total sleep time, Slow Wave Sleep and REM sleep compared with the C group. After acute exercise, there was an increase in Total sleep time and Slow Wave Sleep and a decrease of wakefulness in EEX (+11.10%, +20.29% and -11.25%, respectively) and EX (+5.20%, +11.60% and -8.12%, respectively) groups.CONCLUSION:
These findings suggest that acute physical exercise positively impacts the sleep pattern of rats with TLE, inducing a more consolidated sleep.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Sono
/
Epilepsia do Lobo Temporal
/
Atividade Motora
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article