Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.
J Biol Chem
; 292(38): 15588-15597, 2017 09 22.
Article
em En
| MEDLINE
| ID: mdl-28798238
ABSTRACT
Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mapeamento Cromossômico
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Reparo do DNA
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Escherichia coli
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article