miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-&#954;B in high-grade serous ovarian carcinoma.

Wang, Yuqiong; Zhang, Xiyu; Tang, Wei; Lin, Zhenghong; Xu, Limei; Dong, Ruifen; Li, Yinuo; Li, Jieyin; Zhang, Zaixin; Li, Xiangzhi; Zhao, Ling; Wei, Jian-Jun; Shao, Changshun; Kong, Beihua; Liu, Zhaojian

miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.

Wang, Yuqiong; Zhang, Xiyu; Tang, Wei; Lin, Zhenghong; Xu, Limei; Dong, Ruifen; Li, Yinuo; Li, Jieyin; Zhang, Zaixin; Li, Xiangzhi; Zhao, Ling; Wei, Jian-Jun; Shao, Changshun; Kong, Beihua; Liu, Zhaojian.

Afiliação

Wang Y; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Zhang X; Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, China.
Tang W; Department of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan 250012, China.
Lin Z; Department of Pathogenic Biology, Shandong University School of Medicine, Jinan 250012, China.
Xu L; School of life Science, Chongqing University, Chongqing 401331, China.
Dong R; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Li Y; Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, China.
Li J; Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, China.
Zhang Z; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Li X; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Zhao L; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Wei JJ; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, China.
Shao C; Department of Pathology, Northwestern University School of Medicine, Chicago, IL, USA.
Kong B; Department of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan 250012, China.
Liu Z; Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan 250012, China.

Cell Death Differ ; 24(12): 2089-2100, 2017 12.

Article em En | MEDLINE | ID: mdl-28800130

Assuntos

Cistadenocarcinoma Seroso/metabolismo; MicroRNAs/metabolismo; NF-kappa B/metabolismo; Neoplasias Ovarianas/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Animais; Cistadenocarcinoma Seroso/genética; Cistadenocarcinoma Seroso/patologia; Feminino; Células HEK293; Xenoenxertos; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/genética; NF-kappa B/genética; Gradação de Tumores; Neoplasias Ovarianas/genética; Neoplasias Ovarianas/patologia; Estudos Retrospectivos; Transdução de Sinais; Serina-Treonina Quinases TOR/genética; Transfecção; Proteína 1 do Complexo Esclerose Tuberosa; Proteínas Supressoras de Tumor/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / NF-kappa B / Cistadenocarcinoma Seroso / Proteínas Supressoras de Tumor / MicroRNAs / Serina-Treonina Quinases TOR Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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