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Substrate-Controlled Selectivity Switch in a Three-Component Reaction: A Ag-Catalyzed Strategy for the Synthesis of Functionalized Imidazoles.
Wang, Changcheng; Wang, Enming; Chen, Weixin; Zhang, Lijuan; Zhan, Haiying; Wu, Yuanheng; Cao, Hua.
Afiliação
  • Wang C; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Wang E; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Chen W; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Zhang L; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Zhan H; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Wu Y; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
  • Cao H; School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University , Zhongshan, 528458, P. R. China.
J Org Chem ; 82(17): 9144-9153, 2017 09 01.
Article em En | MEDLINE | ID: mdl-28812340
ABSTRACT
An efficient Ag-catalyzed three-component reaction of amidines, ynals, and alcohols, phenols, or water has been developed. This strategy provides a wide range of substrates and represents a simple process for the preparation of different imidazole derivatives in good yields with high regioselectivities.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article