MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells.

Chen, Ying; Wang, Dan-Dan; Wu, Ye-Ping; Su, Dan; Zhou, Tian-Yi; Gai, Ren-Hua; Fu, Ying-Ying; Zheng, Lin; He, Qiao-Jun; Zhu, Hong; Yang, Bo

Chen, Ying; Wang, Dan-Dan; Wu, Ye-Ping; Su, Dan; Zhou, Tian-Yi; Gai, Ren-Hua; Fu, Ying-Ying; Zheng, Lin; He, Qiao-Jun; Zhu, Hong; Yang, Bo.

Afiliação

Chen Y; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Wang DD; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Wu YP; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Su D; Zhejiang Cancer Hospital, Hangzhou 310022, China.
Zhou TY; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Gai RH; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Fu YY; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zheng L; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
He QJ; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zhu H; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yang B; Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Institute of Pharmacology &Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Br J Cancer ; 117(8): 1192-1201, 2017 Oct 10.

Article em En | MEDLINE | ID: mdl-28817834

Assuntos

Carcinoma/genética; Transição Epitelial-Mesenquimal/genética; Neoplasias Ovarianas/genética; Proteínas Proto-Oncogênicas c-mdm2/genética; Aminoquinolinas/farmacologia; Antígenos CD; Western Blotting; Caderinas/metabolismo; Carcinoma/metabolismo; Carcinoma/patologia; Linhagem Celular Tumoral; Movimento Celular/genética; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Feminino; Imunofluorescência; Técnicas de Silenciamento de Genes; Humanos; Imuno-Histoquímica; Metástase Neoplásica; Estadiamento de Neoplasias; Neoplasias Ovarianas/metabolismo; Neoplasias Ovarianas/patologia; Proteínas Proto-Oncogênicas c-mdm2/efeitos dos fármacos; Proteínas Proto-Oncogênicas c-mdm2/metabolismo; Reação em Cadeia da Polimerase em Tempo Real; Transdução de Sinais; Proteínas Smad/metabolismo; Fatores de Transcrição da Família Snail/genética; Timina/análogos & derivados; Timina/farmacologia; Fator de Crescimento Transformador beta/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Carcinoma / Proteínas Proto-Oncogênicas c-mdm2 / Transição Epitelial-Mesenquimal Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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