Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line.
J Neural Transm (Vienna)
; 125(1): 103-106, 2018 01.
Article
em En
| MEDLINE
| ID: mdl-28821967
ABSTRACT
The neuropeptides oxytocin and arginine vasopressin (AVP) are involved in the regulation of social behavior and cognition. The current study analyzed the effect of oxytocin and AVP on proliferation and differentiation of serotonergic neurons (RN46A cells). Oxytocin did not affect, while 5-10 µM AVP decreased RN46A proliferation. Oxytocin did not significantly alter, while 10 µM AVP decreased the number of cells extending neurites. We found divergent effects of oxytocin and AVP in serotonergic neurons, underscoring their functional differences.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Arginina Vasopressina
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Ocitocina
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Diferenciação Celular
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Proliferação de Células
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Neurônios Serotoninérgicos
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article