Genetic background impacts vaccine-induced reduction of pneumococcal colonization.

Kuipers, Kirsten; van Selm, Saskia; van Opzeeland, Fred; Langereis, Jeroen D; Verhagen, Lilly M; Diavatopoulos, Dimitri A; de Jonge, Marien I

Kuipers, Kirsten; van Selm, Saskia; van Opzeeland, Fred; Langereis, Jeroen D; Verhagen, Lilly M; Diavatopoulos, Dimitri A; de Jonge, Marien I.

Afiliação

Kuipers K; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands.
van Selm S; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands.
van Opzeeland F; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands.
Langereis JD; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands.
Verhagen LM; Department of Pediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital Utrecht, Utrecht, The Netherlands.
Diavatopoulos DA; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands.
de Jonge MI; Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Medical Center, Radboud Center for Infectious Diseases, Nijmegen, The Netherlands. Electronic address: marien.dejonge@radboudumc.nl.

Vaccine ; 35(39): 5235-5241, 2017 09 18.

Article em En | MEDLINE | ID: mdl-28822643

Assuntos

Infecções Pneumocócicas/prevenção & controle; Vacinas Pneumocócicas/uso terapêutico; Streptococcus pneumoniae/imunologia; Administração Intranasal; Animais; Antígenos de Bactérias/imunologia; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Infecções Pneumocócicas/imunologia; Vacinas Pneumocócicas/administração & dosagem; Streptococcus pneumoniae/patogenicidade; Vacinação/métodos

Palavras-chave

Colonization; Distinct nasal cytokine profiles; Intranasal vaccine; Mouse genetic backgrounds; Streptococcus pneumoniae; Vaccine-induced protection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Streptococcus pneumoniae / Vacinas Pneumocócicas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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