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Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson's disease.
Pasquarelli, Noemi; Porazik, Christoph; Bayer, Hanna; Buck, Eva; Schildknecht, Stefan; Weydt, Patrick; Witting, Anke; Ferger, Boris.
Afiliação
  • Pasquarelli N; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88400 Biberach an der Riss, Germany; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany.
  • Porazik C; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88400 Biberach an der Riss, Germany; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany.
  • Bayer H; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany.
  • Buck E; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany.
  • Schildknecht S; In vitro Toxicology and Biomedicine, Department of Biology, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
  • Weydt P; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany; Department of Neurology, Ulm University, Oberer Eselsberg 45, 89081 Ulm, Germany; Department of Neurodegenerative Diseases, Bonn University, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
  • Witting A; Department of Experimental Neurology, Ulm University, Helmholtzstraße 8/1, 89081 Ulm, Germany.
  • Ferger B; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, 88400 Biberach an der Riss, Germany. Electronic address: boris.ferger@boehringer-ingelheim.com.
Neurochem Int ; 110: 14-24, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28826718
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Transtornos Parkinsonianos / Fator Neurotrófico Derivado de Linhagem de Célula Glial / Amidoidrolases / Monoacilglicerol Lipases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dopamina / Transtornos Parkinsonianos / Fator Neurotrófico Derivado de Linhagem de Célula Glial / Amidoidrolases / Monoacilglicerol Lipases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article