Dynamic monitoring of p53 translocation to mitochondria for the analysis of specific inhibitors using luciferase-fragment complementation.

Noda, Natsumi; Awais, Raheela; Sutton, Robert; Awais, Muhammad; Ozawa, Takeaki

Noda, Natsumi; Awais, Raheela; Sutton, Robert; Awais, Muhammad; Ozawa, Takeaki.

Afiliação

Noda N; Department of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Awais R; School of Life Sciences, University of Liverpool, Liverpool, United Kingdom.
Sutton R; NIHR Liverpool Pancreas Biomedical Research Unit, Institute of Translational Medicine, University of Liverpool, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Awais M; NIHR Liverpool Pancreas Biomedical Research Unit, Institute of Translational Medicine, University of Liverpool, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Ozawa T; Department of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Biotechnol Bioeng ; 114(12): 2818-2827, 2017 12.

Article em En | MEDLINE | ID: mdl-28832998

Assuntos

Luciferases; Microscopia de Fluorescência/métodos; Mitocôndrias/metabolismo; Imagem Molecular/métodos; Técnicas de Sonda Molecular; Proteína Supressora de Tumor p53/metabolismo; Células HEK293; Humanos; Mitocôndrias/ultraestrutura; Transporte Proteico/fisiologia

Palavras-chave

luciferase-fragment complementation assays; mitochondria; p53 translocation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Técnicas de Sonda Molecular / Imagem Molecular / Luciferases / Microscopia de Fluorescência / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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