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Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran.
Kumar, Parag; Gordon, Lori A; Brooks, Kristina M; George, Jomy M; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M; Nghiem, Khanh; Lozier, Jay; Hadigan, Colleen; Penzak, Scott R.
Afiliação
  • Kumar P; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA parag.kumar@nih.gov.
  • Gordon LA; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA.
  • Brooks KM; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA.
  • George JM; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA.
  • Kellogg A; Leidos Biomedical Research, Inc., Frederick, Maryland, USA.
  • McManus M; Parker Tide Corporation, Washington, DC, USA.
  • Alfaro RM; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA.
  • Nghiem K; Clinical Center Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.
  • Lozier J; Clinical Center Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.
  • Hadigan C; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Penzak SR; Clinical Pharmacokinetics Research Unit (CPRU), Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, Maryland, USA.
Article em En | MEDLINE | ID: mdl-28848011

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Ritonavir / Cobicistat / Dabigatrana / Mucosa Intestinal Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Ritonavir / Cobicistat / Dabigatrana / Mucosa Intestinal Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article