Histamine and Toll-like receptor ligands synergistically induce endothelial cell gap formation by the extrinsic coagulating pathway.

Yanase, Yuhki; Morioke, Satoshi; Iwamoto, Kazumasa; Takahagi, Shunsuke; Uchida, Kazue; Kawaguchi, Tomoko; Ishii, Kaori; Hide, Izumi; Hide, Michihiro

Yanase, Yuhki; Morioke, Satoshi; Iwamoto, Kazumasa; Takahagi, Shunsuke; Uchida, Kazue; Kawaguchi, Tomoko; Ishii, Kaori; Hide, Izumi; Hide, Michihiro.

Afiliação

Yanase Y; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Morioke S; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Iwamoto K; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Takahagi S; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Uchida K; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Kawaguchi T; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Ishii K; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Hide I; Department of Molecular and Pharmacological Neuroscience, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Hide M; Department of Dermatology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan. Electronic address: ed1h-w1de-road@hiroshima-u.ac.jp.

J Allergy Clin Immunol ; 141(3): 1115-1118.e7, 2018 03.

Article em En | MEDLINE | ID: mdl-28859973

Assuntos

Coagulação Sanguínea/efeitos dos fármacos; Regulação da Expressão Gênica/efeitos dos fármacos; Histamina/farmacologia; Lipopolissacarídeos/toxicidade; Tromboplastina/biossíntese; Receptores Toll-Like/metabolismo; Urticária/metabolismo; Coagulação Sanguínea/genética; Doença Crônica; Células Endoteliais da Veia Umbilical Humana; Humanos; Ligantes; Mastócitos/metabolismo; Mastócitos/patologia; Tromboplastina/genética; Receptores Toll-Like/genética; Urticária/genética; Urticária/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Urticária / Coagulação Sanguínea / Tromboplastina / Histamina / Regulação da Expressão Gênica / Lipopolissacarídeos / Receptores Toll-Like Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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