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Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration.
Plaas, Mario; Seppa, Kadri; Reimets, Riin; Jagomäe, Toomas; Toots, Maarja; Koppel, Tuuliki; Vallisoo, Tuuli; Nigul, Mait; Heinla, Indrek; Meier, Riho; Kaasik, Allen; Piirsoo, Andres; Hickey, Miriam A; Terasmaa, Anton; Vasar, Eero.
Afiliação
  • Plaas M; Institute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia. mario.plaas@ut.ee.
  • Seppa K; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia. mario.plaas@ut.ee.
  • Reimets R; Institute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Jagomäe T; Institute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Toots M; Institute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Koppel T; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia.
  • Vallisoo T; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia.
  • Nigul M; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia.
  • Heinla I; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia.
  • Meier R; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, 14B Ravila Street, Tartu, 50411, Estonia.
  • Kaasik A; Institute of Molecular and Cell Biology, University of Tartu, 23 Riia Street, Tartu, 51010, Estonia.
  • Piirsoo A; Institute of Biomedicine and Translational Medicine, Department of Pharmacology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Hickey MA; Institute of Biomedicine and Translational Medicine, Department of Biomedicine, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Terasmaa A; Institute of Biomedicine and Translational Medicine, Department of Pharmacology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
  • Vasar E; Institute of Biomedicine and Translational Medicine, Department of Physiology, University of Tartu, 19 Ravila Street, Tartu, 50411, Estonia.
Sci Rep ; 7(1): 10220, 2017 08 31.
Article em En | MEDLINE | ID: mdl-28860598
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Wolfram / Proteínas de Ligação a Calmodulina / Deleção de Sequência / Proteínas de Membrana Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Wolfram / Proteínas de Ligação a Calmodulina / Deleção de Sequência / Proteínas de Membrana Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article