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Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3.
Wright, Paul D; Veale, Emma L; McCoull, David; Tickle, David C; Large, Jonathan M; Ococks, Emma; Gothard, Gemma; Kettleborough, Catherine; Mathie, Alistair; Jerman, Jeffrey.
Afiliação
  • Wright PD; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK. Electronic address: Paul.wright@lifearc.org.
  • Veale EL; Medway School of Pharmacy, University of Kent, Anson Building, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • McCoull D; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Tickle DC; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Large JM; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Ococks E; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Gothard G; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Kettleborough C; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
  • Mathie A; Medway School of Pharmacy, University of Kent, Anson Building, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK.
  • Jerman J; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX, UK.
Biochem Biophys Res Commun ; 493(1): 444-450, 2017 11 04.
Article em En | MEDLINE | ID: mdl-28882594
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Potássio / Ativação do Canal Iônico / Canais de Potássio de Domínios Poros em Tandem / Avaliação Pré-Clínica de Medicamentos / Naftalenos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Potássio / Ativação do Canal Iônico / Canais de Potássio de Domínios Poros em Tandem / Avaliação Pré-Clínica de Medicamentos / Naftalenos Idioma: En Ano de publicação: 2017 Tipo de documento: Article