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Hydroxycarbamide in children with sickle cell anaemia after first-dose vs. chronic therapy: pharmacokinetics and predictive models for drug exposure.
Estepp, Jeremie H; Wiczling, Pawel; Moen, Joseph; Kang, Guolian; Mack, Joana Marie; Liem, Robert; Panepinto, Julie A; Garg, Uttam; Kearns, Gregory; Neville, Kathleen A.
Afiliação
  • Estepp JH; Departments of Hematology and Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Wiczling P; Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdansk, Gdansk, Poland.
  • Moen J; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Kang G; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Mack JM; Department of Pediatric Hematology/Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
  • Liem R; Division of Hematology, Oncology, and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Panepinto JA; Section of Pediatric Hematology/Oncology, Medical College of Wisconsin, and Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI, USA.
  • Garg U; Department of Pathology and Laboratory Medicine, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
  • Kearns G; Arkansas Children's Research Institute, Arkansas Children's Hospital, Little Rock, AR, USA.
  • Neville KA; Department of Pediatrics, Section of Clinical Pharmacology and Medical Toxicology, Arkansas Children's Hospital, Little Rock, AR, USA.
Br J Clin Pharmacol ; 84(7): 1478-1485, 2018 07.
Article em En | MEDLINE | ID: mdl-28884840
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroxiureia / Anemia Falciforme / Modelos Biológicos / Antidrepanocíticos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hidroxiureia / Anemia Falciforme / Modelos Biológicos / Antidrepanocíticos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article