Molecular Signature of Tumors with Monoallelic 13q14 Deletion: a Case Series of Spindle Cell Lipoma and Genetically-Related Tumors Demonstrating a Link Between FOXO1 Status and p38 MAPK Pathway.

Uehara, Karina; Ikehara, Fukino; Shibuya, Ryo; Nakazato, Iwao; Oshiro, Mariko; Kiyuna, Masaya; Tanabe, Yasuka; Toyoda, Zensei; Kurima, Kiyoto; Kina, Shinichiro; Hisaoka, Masanori; Kinjo, Takao

Uehara, Karina; Ikehara, Fukino; Shibuya, Ryo; Nakazato, Iwao; Oshiro, Mariko; Kiyuna, Masaya; Tanabe, Yasuka; Toyoda, Zensei; Kurima, Kiyoto; Kina, Shinichiro; Hisaoka, Masanori; Kinjo, Takao.

Afiliação

Uehara K; Division of Morphological Pathology, Department of Basic Laboratory Sciences, School of Health Sciences, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Ikehara F; Division of Morphological Pathology, Department of Basic Laboratory Sciences, School of Health Sciences, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Shibuya R; Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan.
Nakazato I; Department of Pathology, Okinawa Prefectural Nanbu Medical Center and Children's Medical Center, Okinawa, Japan.
Oshiro M; Health Information Management Major, Management and Information Science Division, Faculty of International Studies, Meio University, Okinawa, Japan.
Kiyuna M; Department of Pathology, Tomishiro Chuo Hospital, Okinawa, Japan.
Tanabe Y; Division of Morphological Pathology, Department of Basic Laboratory Sciences, School of Health Sciences, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Toyoda Z; Division of Morphological Pathology, Department of Basic Laboratory Sciences, School of Health Sciences, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan.
Kurima K; Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Kina S; Department of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Hisaoka M; Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan.
Kinjo T; Division of Morphological Pathology, Department of Basic Laboratory Sciences, School of Health Sciences, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, 903-0215, Japan. kinjotko@med.u-ryukyu.ac.jp.

Pathol Oncol Res ; 24(4): 861-869, 2018 Oct.

Article em En | MEDLINE | ID: mdl-28887603

Assuntos

Angiofibroma/genética; Lipoma/genética; Neoplasias de Tecido Muscular/genética; Transdução de Sinais; Transcriptoma; Adulto; Idoso; Idoso de 80 Anos ou mais; Angiofibroma/metabolismo; Cromossomos Humanos Par 13/genética; Feminino; Proteína Forkhead Box O1/genética; Proteína Forkhead Box O1/metabolismo; Deleção de Genes; Humanos; Lipoma/metabolismo; Masculino; Pessoa de Meia-Idade; Neoplasias de Tecido Muscular/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/fisiologia; Adulto Jovem; Proteínas Quinases p38 Ativadas por Mitógeno/genética; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

FOXO 1; Monoallelic 13q14 deletion; RB 1; Reactive oxygen species; p38 MAPK

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Angiofibroma / Transcriptoma / Lipoma / Neoplasias de Tecido Muscular Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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