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Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System.
von Tesmar, Alexander; Hoffmann, Michael; Pippel, Jan; Fayad, Antoine Abou; Dausend-Werner, Stefan; Bauer, Armin; Blankenfeldt, Wulf; Müller, Rolf.
Afiliação
  • von Tesmar A; Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany; German Center for Infection Research (DZIF
  • Hoffmann M; Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany; German Center for Infection Research (DZIF
  • Pippel J; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
  • Fayad AA; Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany; German Center for Infection Research (DZIF
  • Dausend-Werner S; Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany.
  • Bauer A; Sanofi-Aventis Deutschland GmbH, R&D Therapeutic Area Infectious Diseases, Industriepark Höchst G878, 65926 Frankfurt am Main, Germany.
  • Blankenfeldt W; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124 Braunschweig, Germany; Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Spielmannstrasse 7, 38106 Braunschweig, Germany.
  • Müller R; Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany; German Center for Infection Research (DZIF
Cell Chem Biol ; 24(10): 1216-1227.e8, 2017 Oct 19.
Article em En | MEDLINE | ID: mdl-28890318

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Pirróis / Benzodiazepinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Pirróis / Benzodiazepinas Idioma: En Ano de publicação: 2017 Tipo de documento: Article