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Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency.
Di Meo, Ivano; Colombelli, Cristina; Srinivasan, Balaji; de Villiers, Marianne; Hamada, Jeffrey; Jeong, Suh Y; Fox, Rachel; Woltjer, Randall L; Tepper, Pieter G; Lahaye, Liza L; Rizzetto, Emanuela; Harrs, Clara H; de Boer, Theo; van der Zwaag, Marianne; Jenko, Branko; Cusak, Alen; Pahor, Jerca; Kosec, Gregor; Grzeschik, Nicola A; Hayflick, Susan J; Tiranti, Valeria; Sibon, Ody C M.
Afiliação
  • Di Meo I; Division of Molecular Neurogenetics, IRCCS Foundation Neurological Institute "C.Besta" Via Temolo 4, 20126, Milano, Italy.
  • Colombelli C; Division of Molecular Neurogenetics, IRCCS Foundation Neurological Institute "C.Besta" Via Temolo 4, 20126, Milano, Italy.
  • Srinivasan B; Department of Cell Biology, University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • de Villiers M; Department of Biochemistry, Stellenbosch University, Stellenbosch, 7600, South Africa.
  • Hamada J; Departments of Molecular & Medical Genetics and Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Jeong SY; Departments of Molecular & Medical Genetics and Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Fox R; Departments of Molecular & Medical Genetics and Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Woltjer RL; Departments of Molecular & Medical Genetics and Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Tepper PG; Department of Chemical and Pharmaceutical Biology, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Lahaye LL; Department of Cell Biology, University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Rizzetto E; Clinical Pathology and Medical Genetics Unit, Foundation IRCCS-Neurological Institute "Carlo Besta", Milano, Italy.
  • Harrs CH; Department of Cell Biology, University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • de Boer T; Analytical Biochemical Laboratory (ABL), WA Scholtenstraat 7, 9403 AJ, Assen, The Netherlands.
  • van der Zwaag M; Department of Cell Biology, University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Jenko B; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Cusak A; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Pahor J; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Kosec G; Laboratory of Organic and Bioorganic Chemistry, Department of Physical and Organic Chemistry, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • Grzeschik NA; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Hayflick SJ; Department of Cell Biology, University Medical Center Groningen, University of Groningen, Ant. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Tiranti V; Departments of Molecular & Medical Genetics and Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
  • Sibon OCM; Division of Molecular Neurogenetics, IRCCS Foundation Neurological Institute "C.Besta" Via Temolo 4, 20126, Milano, Italy.
Sci Rep ; 7(1): 11260, 2017 09 12.
Article em En | MEDLINE | ID: mdl-28900161

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Panteteína / Fosfotransferases (Aceptor do Grupo Álcool) / Transtornos Heredodegenerativos do Sistema Nervoso / Soro Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Panteteína / Fosfotransferases (Aceptor do Grupo Álcool) / Transtornos Heredodegenerativos do Sistema Nervoso / Soro Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article