Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells <i>in vitro</i> and <i>in vivo</i>.

Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo.

Schmidt, Claudia; Loos, Cornelia; Jin, Lu; Schmiech, Michael; Schmidt, Christoph Q; Gaafary, Menna El; Syrovets, Tatiana; Simmet, Thomas.

Afiliação

Schmidt C; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Loos C; Present address: Rommelag CMO, Sulzbach-Laufen, Germany.
Jin L; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Schmiech M; Present address: Institute of Protein Biochemistry, Ulm University, Ulm, Germany.
Schmidt CQ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Gaafary ME; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Syrovets T; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.
Simmet T; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Ulm, Germany.

Oncotarget ; 8(33): 55147-55161, 2017 Aug 15.

Article em En | MEDLINE | ID: mdl-28903409