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Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
Kågedal, Matts; Gibiansky, Leonid; Xu, Jian; Wang, Xin; Samineni, Divya; Chen, Shang-Chiung; Lu, Dan; Agarwal, Priya; Wang, Bei; Saad, Ola; Koppada, Neelima; Fine, Bernard M; Jin, Jin Y; Girish, Sandhya; Li, Chunze.
Afiliação
  • Kågedal M; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA. kagedal.matts@gene.com.
  • Gibiansky L; QuantPharm LLC, 49 Flints Grove Drive, North Potomac, MD, 20878, USA.
  • Xu J; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Wang X; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Samineni D; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Chen SC; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Lu D; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Agarwal P; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Wang B; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Saad O; BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, 94080, USA.
  • Koppada N; BioAnalytical Sciences, Genentech Inc, South San Francisco, CA, 94080, USA.
  • Fine BM; Clinical Sciences, Genentech Inc, South San Francisco, CA, 94080, USA.
  • Jin JY; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Girish S; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Li C; Clinical Pharmacology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.
J Pharmacokinet Pharmacodyn ; 44(6): 537-548, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28918591
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Valina / Citrulina / Imunoconjugados / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Valina / Citrulina / Imunoconjugados / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article