Mechanisms of accelerated liver fibrosis in HIV-HCV coinfection.
AIDS Rev
; 19(3): 148-155, 2017.
Article
em En
| MEDLINE
| ID: mdl-28926561
ABSTRACT
Although there is evidence that HCV progresses rapidly in HIV/HCV coinfected patients in comparison with HCV monoinfected, the HIV-, HCV- and host/genetic-related factors, as well as the exact mechanisms implicated in this process are not fully elucidated. Furthermore, cure of HCV in those coinfected seems possible with the new antiviral drugs, but high cost as well as insufficient identification, linkage with care and treatment hamper the achievement of this goal. Research on the subject, could reveal an important prognostic marker for the effectiveness of persuasion of patients with HIV/HCV coinfection with a predicted accelerated fibrosis course, in order to facilitate and prioritize, not in terms of guidelines but in the real life situation, their treatment with a medically just framework.
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Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Hepatite C Crônica
/
Coinfecção
/
Cirrose Hepática
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article