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The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.
Shu, Xing-Sheng; Zhao, Yingying; Sun, Yanmei; Zhong, Lan; Cheng, Yingduan; Zhang, Yixiang; Ning, Kaile; Tao, Qian; Wang, Yejun; Ying, Ying.
Afiliação
  • Shu XS; School of Medicine, Health Science Centre, Shenzhen University, Shenzhen, PR China.
  • Zhao Y; Institute of Molecular Medicine, Shenzhen University, Shenzhen, PR China.
  • Sun Y; School of Medicine, Health Science Centre, Shenzhen University, Shenzhen, PR China.
  • Zhong L; School of Medicine, Health Science Centre, Shenzhen University, Shenzhen, PR China.
  • Cheng Y; Department of Gynaecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, PR China.
  • Zhang Y; Department of Urology, The Second Affiliated Hospital of Jinan University, Shenzhen People's Hospital, Shenzhen, PR China.
  • Ning K; Department of Urology, The Second Affiliated Hospital of Jinan University, Shenzhen People's Hospital, Shenzhen, PR China.
  • Tao Q; School of Medicine, Health Science Centre, Shenzhen University, Shenzhen, PR China.
  • Wang Y; Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Centre for Cancer, The Chinese University of Hong Kong, Hong Kong, PR China.
  • Ying Y; School of Medicine, Health Science Centre, Shenzhen University, Shenzhen, PR China.
J Pathol ; 244(1): 36-48, 2018 01.
Article em En | MEDLINE | ID: mdl-28940253
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Doenças Inflamatórias Intestinais / Transdução de Sinais / Neoplasias do Colo / Epigenômica / Imunidade Inata Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Doenças Inflamatórias Intestinais / Transdução de Sinais / Neoplasias do Colo / Epigenômica / Imunidade Inata Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article