Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.

Kulaberoglu, Yavuz; Lin, Kui; Holder, Maxine; Gai, Zhongchao; Gomez, Marta; Assefa Shifa, Belul; Mavis, Merdiye; Hoa, Lily; Sharif, Ahmad A D; Lujan, Celia; Smith, Ewan St John; Bjedov, Ivana; Tapon, Nicolas; Wu, Geng; Hergovich, Alexander

Kulaberoglu, Yavuz; Lin, Kui; Holder, Maxine; Gai, Zhongchao; Gomez, Marta; Assefa Shifa, Belul; Mavis, Merdiye; Hoa, Lily; Sharif, Ahmad A D; Lujan, Celia; Smith, Ewan St John; Bjedov, Ivana; Tapon, Nicolas; Wu, Geng; Hergovich, Alexander.

Afiliação

Kulaberoglu Y; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Lin K; Department of Pharmacology, University of Cambridge, Cambridge, CB2 1PD, UK.
Holder M; State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Gai Z; Apoptosis and Proliferation Control Laboratory, Francis Crick Institute, London, NW1 1BF, UK.
Gomez M; State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Assefa Shifa B; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Mavis M; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Hoa L; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Sharif AAD; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Lujan C; Tumour Suppressor Signalling Network Laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Smith ESJ; Molecular Biology of Cancer laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Bjedov I; Department of Pharmacology, University of Cambridge, Cambridge, CB2 1PD, UK.
Tapon N; Molecular Biology of Cancer laboratory, UCL Cancer Institute, University College London, London, WC1E 6BT, UK.
Wu G; Apoptosis and Proliferation Control Laboratory, Francis Crick Institute, London, NW1 1BF, UK.
Hergovich A; State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. geng.wu@sjtu.edu.cn.

Nat Commun ; 8(1): 695, 2017 09 25.

Article em En | MEDLINE | ID: mdl-28947795

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Drosophila melanogaster/crescimento & desenvolvimento; MAP Quinase Quinase Quinases/metabolismo; Proteínas Serina-Treonina Quinases/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/química; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Animais Geneticamente Modificados; Linhagem Celular; Linhagem Celular Tumoral; Drosophila melanogaster/genética; Via de Sinalização Hippo; Humanos; MAP Quinase Quinase Quinases/genética; Modelos Moleculares; Conformação Proteica; Proteínas Serina-Treonina Quinases/química; Proteínas Serina-Treonina Quinases/genética; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / MAP Quinase Quinase Quinases / Proteínas Adaptadoras de Transdução de Sinal / Drosophila melanogaster Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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