Your browser doesn't support javascript.
loading
Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.
Goto, Akihiko; Tagawa, Yoshihiko; Moriya, Yuu; Sato, Sho; Yamamoto, Masami; Wakabayashi, Takeshi; Tsukamoto, Tetsuya; DeJongh, Joost; van Steeg, Tamara J; Moriwaki, Toshiya; Asahi, Satoru.
Afiliação
  • Goto A; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Tagawa Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Moriya Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Sato S; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Yamamoto M; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Wakabayashi T; Central Nervous System Drug Discovery Unit, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Tsukamoto T; Inflammation Drug Discovery Unit Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • DeJongh J; Leiden Advanced Pharmacokinetics & Pharmacodynamics (LAP&P) Consultants, Leiden, The Netherlands.
  • van Steeg TJ; Leiden Advanced Pharmacokinetics & Pharmacodynamics (LAP&P) Consultants, Leiden, The Netherlands.
  • Moriwaki T; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
  • Asahi S; Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Co. Ltd, Kanagawa, Japan.
Biopharm Drug Dispos ; 38(9): 543-552, 2017 Dec.
Article em En | MEDLINE | ID: mdl-28948605
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Benzofuranos / Tecido Adiposo / Lipídeos / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Benzofuranos / Tecido Adiposo / Lipídeos / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article