Automated cGMP-compliant radiosynthesis of [<sup>18</sup> F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5.

Park, Jun Young; Son, Jeongmin; Yun, Mijin; Ametamey, Simon M; Chun, Joong-Hyun

Automated cGMP-compliant radiosynthesis of [¹⁸ F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5.

Park, Jun Young; Son, Jeongmin; Yun, Mijin; Ametamey, Simon M; Chun, Joong-Hyun.

Afiliação

Park JY; Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Son J; Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Yun M; Department of Nuclear Medicine, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Ametamey SM; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Chun JH; Department of Applied Biosciences of ETH Zurich, Center for Radiopharmaceutical Sciences of ETH, PSI, and USZ, Zurich, Switzerland.

J Labelled Comp Radiopharm ; 61(1): 30-37, 2018 01.

Article em En | MEDLINE | ID: mdl-28948638

Assuntos

Radioisótopos de Flúor/química; Oximas/química; Tomografia por Emissão de Pósitrons/métodos; Piridinas/química; Compostos Radiofarmacêuticos/síntese química; Encéfalo/diagnóstico por imagem; Humanos; Receptor de Glutamato Metabotrópico 5/metabolismo

Palavras-chave

PET imaging; [18F]-(E)-PSS232; automation; fluorine-18; mGlu5; radiopharmaceutical

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Piridinas / Radioisótopos de Flúor / Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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