Optimising ß -lactam Dosing in Neonates: A Review of Pharmacokinetics, Drug Exposure and Pathogens.

Fuchs, Aline; Li, Grace; van den Anker, Johannes N; Bielicki, Julia

Fuchs, Aline; Li, Grace; van den Anker, Johannes N; Bielicki, Julia.

Afiliação

Fuchs A; Paediatric Pharmacology & Pharmacometrics Research, University of Basel Children's Hospital, Basel, Switzerland.
Li G; Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George's, University of London, London, United Kingdom.
van den Anker JN; Paediatric Pharmacology & Pharmacometrics Research, University of Basel Children's Hospital, Basel, Switzerland.
Bielicki J; Intensive Care and Department of Surgery, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands.

Curr Pharm Des ; 23(38): 5805-5838, 2017.

Article em En | MEDLINE | ID: mdl-28950814

Assuntos

Antibacterianos/farmacocinética; Desenvolvimento Infantil/efeitos dos fármacos; Desenvolvimento Infantil/fisiologia; beta-Lactamas/farmacocinética; Antibacterianos/administração & dosagem; Relação Dose-Resposta a Droga; Humanos; Recém-Nascido; Testes de Sensibilidade Microbiana/métodos; Estudos Prospectivos; beta-Lactamas/administração & dosagem

Palavras-chave

PK/PD index; Paediatrics; carbapenems.; cephalosporins; dosing optimization; penicillins; pharmacodynamics; pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenvolvimento Infantil / Beta-Lactamas / Antibacterianos Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Newborn Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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