Palladium(II)/N-Heterocyclic Carbene-Catalyzed Direct C-H Acylation of Heteroarenes with N-Acylsaccharins.
Org Lett
; 19(19): 5486-5489, 2017 10 06.
Article
em En
| MEDLINE
| ID: mdl-28953407
ABSTRACT
N-Acylsaccharin represents a facile acyl group transfer agent to heteroarenes in the presence of Pd(II)/NHC complexes appended with a pyrene unit. Catalytic acylation of heteroarenes was enhanced by the noncovalent interaction between the pyrene unit and substrates. High functional group tolerance, broad substrate scope, and moderate to good yields of 2-acylated azoles are added features of this method.
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MEDLINE
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article