Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat.

Vargas, Vladimir E; Gurung, Sunam; Grant, Benjamin; Hyatt, Kimberly; Singleton, Krista; Myers, Sarah M; Saunders, Debra; Njoku, Charity; Towner, Rheal; Myers, Dean A

Vargas, Vladimir E; Gurung, Sunam; Grant, Benjamin; Hyatt, Kimberly; Singleton, Krista; Myers, Sarah M; Saunders, Debra; Njoku, Charity; Towner, Rheal; Myers, Dean A.

Afiliação

Vargas VE; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Gurung S; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Grant B; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Hyatt K; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Singleton K; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Myers SM; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.
Saunders D; Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.
Njoku C; Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.
Towner R; Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.
Myers DA; Departments of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.

PLoS One ; 12(9): e0185272, 2017.

Article em En | MEDLINE | ID: mdl-28957383

Assuntos

Hiperfagia/sangue; Hiperfagia/complicações; Hipóxia/sangue; Hipóxia/complicações; Leptina/sangue; Obesidade/sangue; Obesidade/complicações; Tecido Adiposo/metabolismo; Animais; Animais Recém-Nascidos; Ansiedade/sangue; Ansiedade/complicações; Núcleo Arqueado do Hipotálamo/metabolismo; Comportamento Animal; Dieta; Medo; Comportamento Alimentar; Feminino; Peso Fetal; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Imageamento por Ressonância Magnética; Masculino; Fenômenos Fisiológicos da Nutrição Materna; Aprendizagem em Labirinto; Atividade Motora; Gravidez; Ratos Sprague-Dawley; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo; Água; Desmame; alfa-MSH/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hiperfagia / Leptina / Hipóxia / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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