[Modified Jujing No.2 Decoction for varicocele-induced male infertility].
Zhonghua Nan Ke Xue
; 22(7): 645-648, 2016 07.
Article
em Zh
| MEDLINE
| ID: mdl-28965385
ABSTRACT
Objective:
To investigate the clinical effect of Jujing No.2 Decoction on male infertility induced by varicocele.METHODS:
We equally randomized 70 male patients with varicocele-induced infertility into a treatment group and a control group, the former treated with modified Jujing No.2 Decoction (1 dose a day, bid) and the latter given Danshen Tablets (4 tablets once, tid) plus Liu Wei Di Huang Wan (8 pills once, tid), both for 3 months. We examined the spermatic veins of the patients by ultrasonography and performed seminal analysis before and after medication.RESULTS:
Compared with the controls, the patients in the treatment group showed significant improvement after medication in sperm concentration (ï¼»12.35±2.12ï¼½ vs ï¼»18.56±4.16ï¼½ ×106/ml, P<0.05), progressively motile sperm (ï¼»16.18±6.34ï¼½ vs ï¼»24.63±8.51ï¼½ %, P<0.05), and morphologically normal sperm (ï¼»11.59±5.31ï¼½ vs ï¼»14.17±6.02ï¼½ %, P<0.05). In the control group, sperm concentration was increased from (12.29±2.07) ×106/ml at the baseline to (13.13±3.13) ×106/ml after medication, progressively motile sperm from (16.13±6.45) % to (20.55±7.30) % (P<0.05), and morphologically normal sperm from (11.62±5.35) % to (12.69±5.77) %. The total effectiveness rate was significantly higher in the treatment than in the control group (71.88% vs 46.67%, P<0.05). The inner diameter of the left spermatic vein was decreased from (0.32±0.05) mm at the baseline to ï¼»0.26±0.05ï¼½ mm after medication in the treatment group (P<0.05) and from (0.32±0.03) mm to (0.29±0.04) mm in the control (P<0.05), with statistically significant difference between the two groups after medication (P<0.05).CONCLUSIONS:
Jujing No.2 Decoction is effective in the treatment of varicocele-induced male infertility.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Varicocele
/
Medicamentos de Ervas Chinesas
/
Infertilidade Masculina
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Limite:
Humans
/
Male
Idioma:
Zh
Ano de publicação:
2016
Tipo de documento:
Article