Secukinumab sustains improvement in signs and symptoms of psoriatic arthritis: 2 year results from the phase 3 FUTURE 2 study.

McInnes, Iain B; Mease, Philip J; Ritchlin, Christopher T; Rahman, Proton; Gottlieb, Alice B; Kirkham, Bruce; Kajekar, Radhika; Delicha, Eumorphia-Maria; Pricop, Luminita; Mpofu, Shephard

McInnes, Iain B; Mease, Philip J; Ritchlin, Christopher T; Rahman, Proton; Gottlieb, Alice B; Kirkham, Bruce; Kajekar, Radhika; Delicha, Eumorphia-Maria; Pricop, Luminita; Mpofu, Shephard.

Afiliação

McInnes IB; Institute of Infection Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Mease PJ; Division of Rheumatology Clinical Research, Swedish Medical Centre and University of Washington, Seattle, WA.
Ritchlin CT; Allergy/Immunology and Rheumatology Division, University of Rochester, Rochester, NY, USA.
Rahman P; Faculty of Medicine, Memorial University, St. John's, NL, Canada.
Gottlieb AB; Department of Dermatology, New York Medical College, Valhalla, NY, USA.
Kirkham B; Rheumatology Department, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Kajekar R; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Delicha EM; Novartis Pharma, Basel, Switzerland.
Pricop L; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
Mpofu S; Novartis Pharma, Basel, Switzerland.

Rheumatology (Oxford) ; 56(11): 1993-2003, 2017 11 01.

Article em En | MEDLINE | ID: mdl-28968735

Assuntos

Anticorpos Monoclonais/uso terapêutico; Antirreumáticos/uso terapêutico; Artrite Psoriásica/tratamento farmacológico; Anticorpos Monoclonais Humanizados; Artrite Psoriásica/metabolismo; Artrite Psoriásica/fisiopatologia; Proteína C-Reativa/metabolismo; Diarreia/induzido quimicamente; Método Duplo-Cego; Quimioterapia Combinada; Glucocorticoides/uso terapêutico; Humanos; Modelos Logísticos; Estudos Longitudinais; Metotrexato/uso terapêutico; Nasofaringite/induzido quimicamente; Medidas de Resultados Relatados pelo Paciente; Qualidade de Vida; Infecções Respiratórias/induzido quimicamente; Índice de Gravidade de Doença; Resultado do Tratamento

Palavras-chave

anti-TNF therapy; biological therapies; efficacy; interleukin; joints; long term; psoriatic arthritis; safety; spondyloarthritis; swelling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Psoriásica / Antirreumáticos / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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