Novel features and enhancements in BioBin, a tool for the biologically inspired binning and association analysis of rare variants.
Bioinformatics
; 34(3): 527-529, 2018 02 01.
Article
em En
| MEDLINE
| ID: mdl-28968757
ABSTRACT
Motivation BioBin is an automated bioinformatics tool for the multi-level biological binning of sequence variants. Herein, we present a significant update to BioBin which expands the software to facilitate a comprehensive rare variant analysis and incorporates novel features and analysis enhancements. Results:
In BioBin 2.3, we extend our software tool by implementing statistical association testing, updating the binning algorithm, as well as incorporating novel analysis features providing for a robust, highly customizable, and unified rare variant analysis tool. Availability and implementation The BioBin software package is open source and freely available to users at http//www.ritchielab.com/software/biobin-download. Contact mdritchie@geisinger.edu. Supplementary information Supplementary data are available at Bioinformatics online.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Software
/
Estudos de Associação Genética
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article