Berchemiosides A-C, 2-Acetoxy-ω-phenylpentaene Fatty Acid Triglycosides from the Unripe Fruits of Berchemia berchemiifolia.
J Nat Prod
; 80(10): 2778-2786, 2017 10 27.
Article
em En
| MEDLINE
| ID: mdl-28972762
ABSTRACT
Three compounds in a new class of 2-acetoxy-ω-phenylpentaene fatty acid triglycosides, berchemiosides A-C (1-3), and a biosynthetically related phenolic glycoside (4) were isolated from the unripe fruits of Berchemia berchemiifolia, along with three flavonoid 5-O-diglycosides (5-7) and three known flavonoids (8-10). Their chemical structures including absolute configurations were determined by spectroscopic analysis in combination with chemical derivatization. The pentaene group of 1 was found to have (6E,8E,10Z,12Z,14E)-geometry, whereas those of 2 and 3 exhibited all-E geometries. The isolated compounds were examined for their cytotoxicity and xanthine oxidase (XO) inhibitory activity; only compound 7 showed weak XO inhibitory activity.
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1
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
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Rhamnaceae
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Ácidos Graxos Insaturados
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Frutas
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Glicosídeos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article