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Neutral evolution of drug resistant colorectal cancer cell populations is independent of their KRAS status.
Blagoev, Krastan B; Wilkerson, Julia; Burotto, Mauricio; Kim, Chul; Espinal-Domínguez, Edward; García-Alfonso, Pilar; Alimchandani, Meghna; Miettinen, Markku; Blanco-Codesido, Montserrat; Fojo, Tito.
Afiliação
  • Blagoev KB; Physics of Living Systems, National Science Foundation, Arlington, Virginia, United States of America.
  • Wilkerson J; Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America.
  • Burotto M; Medical Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.
  • Kim C; Departamento de Oncologia, Clinica Alemana de Santiago, Santiago, Chile.
  • Espinal-Domínguez E; Medical Oncology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.
  • García-Alfonso P; Departamento de Oncologia Medica, Gregorio Marañon University Hospital, Madrid, Spain.
  • Alimchandani M; Departamento de Oncologia Medica, Gregorio Marañon University Hospital, Madrid, Spain.
  • Miettinen M; Center for Biologics Evaluation and Research, US Food and Drug Administration (USFDA), Silver Spring, Maryland, United States of America.
  • Blanco-Codesido M; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America.
  • Fojo T; Departamento de Oncologia Medica, Gregorio Marañon University Hospital, Madrid, Spain.
PLoS One ; 12(10): e0175484, 2017.
Article em En | MEDLINE | ID: mdl-28981524
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) / Resistencia a Medicamentos Antineoplásicos / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article