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Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA).
Rademacher, Sebastian; Verheijen, Bert M; Hensel, Niko; Peters, Miriam; Bora, Gamze; Brandes, Gudrun; Vieira de Sá, Renata; Heidrich, Natascha; Fischer, Silke; Brinkmann, Hella; van der Pol, W Ludo; Wirth, Brunhilde; Pasterkamp, R Jeroen; Claus, Peter.
Afiliação
  • Rademacher S; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • Verheijen BM; Center for Systems Neuroscience (ZSN), Hannover, Germany.
  • Hensel N; Department of Translational Neuroscience & MIND Facility, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
  • Peters M; Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
  • Bora G; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • Brandes G; Institute of Human Genetics, Center for Molecular Medicine Cologne, Center for Rare Diseases Cologne, and Institute of Genetics, University of Cologne, 50931 Cologne, Germany.
  • Vieira de Sá R; Department of Medical Biology, Faculty of Medicine, Hacettepe University, 06100 Ankara, Turkey.
  • Heidrich N; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • Fischer S; Department of Translational Neuroscience & MIND Facility, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
  • Brinkmann H; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • van der Pol WL; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • Wirth B; Institute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
  • Pasterkamp RJ; Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
  • Claus P; Institute of Human Genetics, Center for Molecular Medicine Cologne, Center for Rare Diseases Cologne, and Institute of Genetics, University of Cologne, 50931 Cologne, Germany.
Hum Mol Genet ; 26(20): 3946-3959, 2017 10 15.
Article em En | MEDLINE | ID: mdl-29016853
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citoesqueleto de Actina / Glicoproteínas de Membrana / Atrofia Muscular Espinal / Moléculas de Adesão Celular Neuronais / Metaloproteases / Neurônios Motores / Proteínas do Tecido Nervoso Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citoesqueleto de Actina / Glicoproteínas de Membrana / Atrofia Muscular Espinal / Moléculas de Adesão Celular Neuronais / Metaloproteases / Neurônios Motores / Proteínas do Tecido Nervoso Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article