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Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing.
Piantadosi, Anne; Kanjilal, Sanjat; Ganesh, Vijay; Khanna, Arjun; Hyle, Emily P; Rosand, Jonathan; Bold, Tyler; Metsky, Hayden C; Lemieux, Jacob; Leone, Michael J; Freimark, Lisa; Matranga, Christian B; Adams, Gordon; McGrath, Graham; Zamirpour, Siavash; Telford, Sam; Rosenberg, Eric; Cho, Tracey; Frosch, Matthew P; Goldberg, Marcia B; Mukerji, Shibani S; Sabeti, Pardis C.
Afiliação
  • Piantadosi A; Division of Infectious Diseases, Massachusetts General Hospital.
  • Kanjilal S; Harvard Medical School, Boston.
  • Ganesh V; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge.
  • Khanna A; Division of Infectious Diseases, Massachusetts General Hospital.
  • Hyle EP; Harvard Medical School, Boston.
  • Rosand J; Department of Neurology, Massachusetts General Hospital, Boston.
  • Bold T; Department of Neurology, Massachusetts General Hospital, Boston.
  • Metsky HC; Division of Infectious Diseases, Massachusetts General Hospital.
  • Lemieux J; Harvard Medical School, Boston.
  • Leone MJ; Department of Neurology, Massachusetts General Hospital, Boston.
  • Freimark L; Division of Infectious Diseases, Massachusetts General Hospital.
  • Matranga CB; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge.
  • Adams G; Department of Electrical Engineering and Computer Science, MIT, Cambridge.
  • McGrath G; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge.
  • Zamirpour S; Department of Medicine, Massachusetts General Hospital, Boston.
  • Telford S; Department of Neurology, Massachusetts General Hospital, Boston.
  • Rosenberg E; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge.
  • Cho T; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge.
  • Frosch MP; Division of Infectious Diseases, Massachusetts General Hospital.
  • Goldberg MB; Division of Infectious Diseases, Massachusetts General Hospital.
  • Mukerji SS; Harvard University, Cambridge.
  • Sabeti PC; Tufts School of Veterinary Medicine, North Grafton.
Clin Infect Dis ; 66(5): 789-792, 2018 02 10.
Article em En | MEDLINE | ID: mdl-29020227
ABSTRACT
We describe a patient with severe and progressive encephalitis of unknown etiology. We performed rapid metagenomic sequencing from cerebrospinal fluid and identified Powassan virus, an emerging tick-borne flavivirus that has been increasingly detected in the United States.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encefalite Transmitida por Carrapatos / Vírus da Encefalite Transmitidos por Carrapatos / Metagenômica Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encefalite Transmitida por Carrapatos / Vírus da Encefalite Transmitidos por Carrapatos / Metagenômica Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article