Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for <i>GABBR1</i>.

Vangeel, Elise Beau; Pishva, Ehsan; Hompes, Titia; van den Hove, Daniel; Lambrechts, Diether; Allegaert, Karel; Freson, Kathleen; Izzi, Benedetta; Claes, Stephan

Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1.

Vangeel, Elise Beau; Pishva, Ehsan; Hompes, Titia; van den Hove, Daniel; Lambrechts, Diether; Allegaert, Karel; Freson, Kathleen; Izzi, Benedetta; Claes, Stephan.

Afiliação

Vangeel EB; Department of Neurosciences, Genetic Research About Stress and Psychiatry (GRASP), KU Leuven, Leuven, Belgium.
Pishva E; Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology (CMVB), KU Leuven, Leuven, Belgium.
Hompes T; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.
van den Hove D; University of Exeter Medical School, University of Exeter, Exeter, UK.
Lambrechts D; Department of Neurosciences, Genetic Research About Stress and Psychiatry (GRASP), KU Leuven, Leuven, Belgium.
Allegaert K; University Psychiatric Center, Leuven, Belgium.
Freson K; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.
Izzi B; Department of Psychiatry, Psychosomatics and Psychotherapy, Laboratory of Translational Neuroscience, University of Wuerzburg, Wuerzburg, Germany.
Claes S; Department of Oncology, Laboratory of Translational Genetics, KU Leuven, Leuven, Belgium.

Clin Epigenetics ; 9: 107, 2017.

Article em En | MEDLINE | ID: mdl-29026448

Assuntos

Ansiedade/genética; Metilação de DNA; Complicações na Gravidez/psicologia; Efeitos Tardios da Exposição Pré-Natal/genética; Receptores de GABA-B/genética; Ansiedade/metabolismo; Epigênese Genética; Feminino; Predisposição Genética para Doença; Estudo de Associação Genômica Ampla; Humanos; Hidrocortisona/sangue; Lactente; Recém-Nascido; Masculino; Gravidez; Complicações na Gravidez/metabolismo; Efeitos Tardios da Exposição Pré-Natal/sangue; Vacinação/psicologia

Palavras-chave

DNA methylation; GABBR1; Gender differences; HPA axis; Pregnancy anxiety; Prenatal stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ansiedade / Complicações na Gravidez / Efeitos Tardios da Exposição Pré-Natal / Receptores de GABA-B / Metilação de DNA Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Male / Newborn / Pregnancy Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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