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MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.
Lemaçon, Delphine; Jackson, Jessica; Quinet, Annabel; Brickner, Joshua R; Li, Shan; Yazinski, Stephanie; You, Zhongsheng; Ira, Grzegorz; Zou, Lee; Mosammaparast, Nima; Vindigni, Alessandro.
Afiliação
  • Lemaçon D; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Jackson J; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Quinet A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA.
  • Brickner JR; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Li S; Department of Cell Biology and Physiology, Washington University School of Medicine, Campus Box 8228, 660S. Euclid Ave., St Louis, MO, 63110, USA.
  • Yazinski S; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
  • You Z; Department of Cell Biology and Physiology, Washington University School of Medicine, Campus Box 8228, 660S. Euclid Ave., St Louis, MO, 63110, USA.
  • Ira G; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
  • Zou L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02129, USA.
  • Mosammaparast N; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Vindigni A; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, 63104, USA. avindign@slu.edu.
Nat Commun ; 8(1): 860, 2017 10 16.
Article em En | MEDLINE | ID: mdl-29038425
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte / Proteína BRCA2 / Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / DNA Polimerase III / Endonucleases / Exodesoxirribonucleases / Proteína Homóloga a MRE11 Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte / Proteína BRCA2 / Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / DNA Polimerase III / Endonucleases / Exodesoxirribonucleases / Proteína Homóloga a MRE11 Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article