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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew, Robert J; Fernandez, Celia G; Stanley, Molly; Jiang, Hong; Nguyen, Phuong; Rice, Richard C; Buggia-Prévot, Virginie; De Rossi, Pierre; Vetrivel, Kulandaivelu S; Lamb, Raza; Argemi, Arnau; Allaert, Emilie S; Rathbun, Elle M; Krause, Sofia V; Wagner, Steven L; Parent, Angèle T; Holtzman, David M; Thinakaran, Gopal.
Afiliação
  • Andrew RJ; Department of Neurobiology, The University of Chicago, Chicago, IL 60637.
  • Fernandez CG; Department of Neurology, The University of Chicago, Chicago, IL 60637.
  • Stanley M; Department of Pathology, The University of Chicago, Chicago, IL 60637.
  • Jiang H; Department of Neurobiology, The University of Chicago, Chicago, IL 60637.
  • Nguyen P; Department of Neurology, The University of Chicago, Chicago, IL 60637.
  • Rice RC; Department of Pathology, The University of Chicago, Chicago, IL 60637.
  • Buggia-Prévot V; Hope Center for Neurological Disorders, Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
  • De Rossi P; Knight Alzheimer's Disease Research Center, Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
  • Vetrivel KS; Hope Center for Neurological Disorders, Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
  • Lamb R; Knight Alzheimer's Disease Research Center, Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
  • Argemi A; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093.
  • Allaert ES; Department of Neurobiology, The University of Chicago, Chicago, IL 60637.
  • Rathbun EM; Department of Neurology, The University of Chicago, Chicago, IL 60637.
  • Krause SV; Department of Pathology, The University of Chicago, Chicago, IL 60637.
  • Wagner SL; Department of Neurobiology, The University of Chicago, Chicago, IL 60637.
  • Parent AT; Department of Neurology, The University of Chicago, Chicago, IL 60637.
  • Holtzman DM; Department of Pathology, The University of Chicago, Chicago, IL 60637.
  • Thinakaran G; Department of Neurobiology, The University of Chicago, Chicago, IL 60637.
Proc Natl Acad Sci U S A ; 114(45): E9665-E9674, 2017 11 07.
Article em En | MEDLINE | ID: mdl-29078331
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Amiloide / Transtornos da Memória Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Aspártico Endopeptidases / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Amiloide / Transtornos da Memória Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article