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Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.
Cheng, Jiqiu; Demeulemeester, Jonas; Wedge, David C; Vollan, Hans Kristian M; Pitt, Jason J; Russnes, Hege G; Pandey, Bina P; Nilsen, Gro; Nord, Silje; Bignell, Graham R; White, Kevin P; Børresen-Dale, Anne-Lise; Campbell, Peter J; Kristensen, Vessela N; Stratton, Michael R; Lingjærde, Ole Christian; Moreau, Yves; Van Loo, Peter.
Afiliação
  • Cheng J; Department of Electrical Engineering (ESAT) and iMinds Future Health Department, University of Leuven, Kasteelpark Arenberg 10, B-3001, Leuven, Belgium.
  • Demeulemeester J; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, N-0310, Oslo, Norway.
  • Wedge DC; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Vollan HKM; Department of Human Genetics, University of Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Pitt JJ; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Russnes HG; Big Data Institute, University of Oxford, Old Road, Oxford, OX3 7LF, UK.
  • Pandey BP; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, N-0310, Oslo, Norway.
  • Nilsen G; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Nord S; Institute for Genomics and Systems Biology, University of Chicago, 900 East 57th Street, Chicago, IL, 60637, USA.
  • Bignell GR; Committee on Genetics, Genomics, and Systems Biology, University of Chicago, 920 East 58th Street, Chicago, IL, 60637, USA.
  • White KP; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, N-0310, Oslo, Norway.
  • Børresen-Dale AL; Department of Pathology, Oslo University Hospital Radiumhospitalet, N-0310, Oslo, Norway.
  • Campbell PJ; Department of Electrical Engineering (ESAT) and iMinds Future Health Department, University of Leuven, Kasteelpark Arenberg 10, B-3001, Leuven, Belgium.
  • Kristensen VN; Department of Informatics and Centre for Cancer Biomedicine, University of Oslo, N-0424, Oslo, Norway.
  • Stratton MR; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, N-0310, Oslo, Norway.
  • Lingjærde OC; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Moreau Y; Institute for Genomics and Systems Biology, University of Chicago, 900 East 57th Street, Chicago, IL, 60637, USA.
  • Van Loo P; Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, Chicago, IL, 60637, USA.
Nat Commun ; 8(1): 1221, 2017 10 31.
Article em En | MEDLINE | ID: mdl-29089486
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genes Supressores de Tumor / Deleção de Genes / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genes Supressores de Tumor / Deleção de Genes / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article