A Case of Congenital Infantile Fibrosarcoma of the Bowel Presenting as a Neonatal Intussusception.
Pathol Int
; 67(12): 644-648, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-29090505
ABSTRACT
Neonatal intussusception of the intestinal tract is rare. However, most neonatal intussusceptions have an organic lead point. For the lead point to be a neoplasm is extremely rare. We report a case that presented with neonatal intussusception with a congenital infantile fibrosarcoma as the lead point. The detection of ETV6-NTRK3 gene fusion was useful, although the definitive diagnosis was achieved by a comprehensive evaluation including this gene analysis, standard histology and immunohistochemistry. Neonatal intussusception should be suspected to be caused by a neoplasm. If pathological diagnosis is difficult, molecular analysis should be utilized to diagnose congenital infantile fibrosarcoma.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas Repressoras
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Receptor trkC
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Proteínas Proto-Oncogênicas c-ets
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Fibrossarcoma
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Intussuscepção
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
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Newborn
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article