Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation.

Kentala, Henriikka; Koponen, Annika; Kivelä, Annukka M; Andrews, Robert; Li, ChunHei; Zhou, You; Olkkonen, Vesa M

Kentala, Henriikka; Koponen, Annika; Kivelä, Annukka M; Andrews, Robert; Li, ChunHei; Zhou, You; Olkkonen, Vesa M.

Afiliação

Kentala H; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
Koponen A; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
Kivelä AM; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
Andrews R; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff University, Cardiff, United Kingdom.
Li C; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff University, Cardiff, United Kingdom.
Zhou Y; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff University, Cardiff, United Kingdom.
Olkkonen VM; Minerva Foundation Institute for Medical Research, Helsinki, Finland.

FASEB J ; 32(3): 1281-1295, 2018 03.

Article em En | MEDLINE | ID: mdl-29092904

Assuntos

Citoesqueleto de Actina/fisiologia; Movimento Celular; Hepatócitos/fisiologia; Receptores de Esteroides/metabolismo; Sistemas CRISPR-Cas; Adesão Celular; Proliferação de Células; Técnicas de Inativação de Genes; Hepatócitos/citologia; Humanos; Receptores de Esteroides/genética; Transdução de Sinais

Palavras-chave

CRISPR-Cas9; F-actin; OSBPL2; RNA sequencing; interactome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citoesqueleto de Actina / Receptores de Esteroides / Movimento Celular / Hepatócitos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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