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Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity.
Smith, Reuben L; Tan, Josephine M E; Jonker, Martijs J; Jongejan, Aldo; Buissink, Thomas; Veldhuijzen, Steve; van Kampen, Antoine H C; Brul, Stanley; van der Spek, Hans.
Afiliação
  • Smith RL; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • Tan JME; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • Jonker MJ; RNA Biology & Applied Bioinformatics, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • Jongejan A; Bioinformatics Laboratory, Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center (AMC), Amsterdam, The Netherlands.
  • Buissink T; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • Veldhuijzen S; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • van Kampen AHC; Bioinformatics Laboratory, Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center (AMC), Amsterdam, The Netherlands.
  • Brul S; Biosystems data analysis, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
  • van der Spek H; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.
PLoS One ; 12(11): e0187424, 2017.
Article em En | MEDLINE | ID: mdl-29095935

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / DNA Polimerase Dirigida por DNA / Mitocôndrias Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / DNA Polimerase Dirigida por DNA / Mitocôndrias Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article