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Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease.
Nwankwo, Jennifer O; Gremmel, Thomas; Gerrits, Anja J; Mithila, Farha J; Warburton, Rod R; Hill, Nicholas S; Lu, Yunzhe; Richey, Lauren J; Jakubowski, Joseph A; Frelinger, Andrew L; Chishti, Athar H.
Afiliação
  • Nwankwo JO; Graduate Program in Pharmacology and Experimental Therapeutics, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA, USA.
  • Gremmel T; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Gerrits AJ; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Mithila FJ; Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA.
  • Warburton RR; Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA.
  • Hill NS; Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA.
  • Lu Y; Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA.
  • Richey LJ; Division of Laboratory Animal Medicine, Tufts University, Boston, MA, USA.
  • Jakubowski JA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
  • Frelinger AL; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Chishti AH; Graduate Program in Pharmacology and Experimental Therapeutics, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA, USA; Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA. Electronic address:
Thromb Res ; 160: 58-65, 2017 Dec.
Article em En | MEDLINE | ID: mdl-29101791

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Plaquetas / Calpaína / Ativação Plaquetária / Anemia Falciforme Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Plaquetas / Calpaína / Ativação Plaquetária / Anemia Falciforme Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article