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PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1.
Liu, Lili; Kong, Muwen; Gassman, Natalie R; Freudenthal, Bret D; Prasad, Rajendra; Zhen, Stephanie; Watkins, Simon C; Wilson, Samuel H; Van Houten, Bennett.
Afiliação
  • Liu L; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Kong M; The University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Gassman NR; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Freudenthal BD; The University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Prasad R; Genomic Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
  • Zhen S; Genomic Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
  • Watkins SC; Genomic Integrity & Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
  • Wilson SH; Department of Chemistry, Skidmore College, Saratoga Springs, NY 12866, USA.
  • Van Houten B; Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Nucleic Acids Res ; 45(22): 12834-12847, 2017 Dec 15.
Article em En | MEDLINE | ID: mdl-29121337
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA Liase (Sítios Apurínicos ou Apirimidínicos) / Reparo do DNA / Poli(ADP-Ribose) Polimerase-1 Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / DNA Liase (Sítios Apurínicos ou Apirimidínicos) / Reparo do DNA / Poli(ADP-Ribose) Polimerase-1 Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article