Metabolic profile of Kudiezi injection in rats by UHPLC coupled with Fourier transform ion cyclotron resonance mass spectrometry.

Zhang, Jingdan; Zhang, Xiaoxue; Zhao, Yangyang; Song, Aihua; Sun, Wei; Yin, Ran

Zhang, Jingdan; Zhang, Xiaoxue; Zhao, Yangyang; Song, Aihua; Sun, Wei; Yin, Ran.

Afiliação

Zhang J; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Zhang X; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Zhao Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Song A; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Sun W; School of Medical Devices, Shenyang Pharmaceutical University, Shenyang, China.
Yin R; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.

J Sep Sci ; 41(3): 774-788, 2018 Feb.

Article em En | MEDLINE | ID: mdl-29131518

Assuntos

Cromatografia Líquida de Alta Pressão; Medicamentos de Ervas Chinesas/química; Análise de Fourier; Espectrometria de Massas; Metaboloma; Animais; Bile/química; Ciclotrons; Fezes/química; Hidrólise; Hidroxilação; Injeções; Masculino; Plasma/química; Ratos; Ratos Sprague-Dawley; Urina/química

Palavras-chave

Fourier transform ion cyclotron resonance mass spectrometry; Kudiezi injection; metabolic profile; traditional Chinese medicine; ultra high performance liquid chromatography

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Medicamentos de Ervas Chinesas / Cromatografia Líquida de Alta Pressão / Metaboloma / Análise de Fourier Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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