Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9<sup>+</sup> and IL-13<sup>+</sup> type 2 innate lymphoid cell subpopulations.

Verma, Mukesh; Liu, Sucai; Michalec, Lidia; Sripada, Anand; Gorska, Magdalena M; Alam, Rafeul

Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9⁺ and IL-13⁺ type 2 innate lymphoid cell subpopulations.

Verma, Mukesh; Liu, Sucai; Michalec, Lidia; Sripada, Anand; Gorska, Magdalena M; Alam, Rafeul.

Afiliação

Verma M; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo.
Liu S; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo.
Michalec L; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo; Department of Cytobiology and Proteomics, Medical University of Lodz, Lodz, Poland.
Sripada A; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo.
Gorska MM; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo; School of Medicine, University of Colorado Denver, Denver, Colo.
Alam R; Department of Medicine, Division of Allergy & Immunology, National Jewish Health, Denver, Colo; School of Medicine, University of Colorado Denver, Denver, Colo. Electronic address: alamr@njhealth.org.

J Allergy Clin Immunol ; 142(3): 793-803.e8, 2018 09.

Article em En | MEDLINE | ID: mdl-29132961

Assuntos

Asma/imunologia; Citocinas/imunologia; Proteína 1 Semelhante a Receptor de Interleucina-1/imunologia; Interleucina-13/imunologia; Interleucina-33/imunologia; Interleucina-9/imunologia; Animais; Asma/fisiopatologia; Líquido da Lavagem Broncoalveolar/imunologia; Feminino; Proteína 1 Semelhante a Receptor de Interleucina-1/genética; Linfócitos/imunologia; Camundongos Endogâmicos BALB C; Camundongos Knockout; Muco/imunologia; Hipersensibilidade Respiratória; Linfopoietina do Estroma do Timo

Palavras-chave

Asthma; IL-33 receptor; IL-9; mast cells; thymic stromal lymphopoietin; type 2 innate lymphoid cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Citocinas / Interleucina-9 / Interleucina-13 / Interleucina-33 / Proteína 1 Semelhante a Receptor de Interleucina-1 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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