Your browser doesn't support javascript.
loading
Design, synthesis, and evaluation of A-ring-modified lamellarin N analogues as noncovalent inhibitors of the EGFR T790M/L858R mutant.
Fukuda, Tsutomu; Umeki, Teppei; Tokushima, Keiji; Xiang, Gao; Yoshida, Yuki; Ishibashi, Fumito; Oku, Yusuke; Nishiya, Naoyuki; Uehara, Yoshimasa; Iwao, Masatomo.
Afiliação
  • Fukuda T; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Umeki T; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Tokushima K; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Xiang G; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Yoshida Y; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Ishibashi F; Division of Marine Life Science and Biochemistry, Graduate School of Fisheries and Environmental Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
  • Oku Y; Department of Integrated Information for Pharmaceutical Sciences, Iwate Medical University School of Pharmacy, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
  • Nishiya N; Department of Integrated Information for Pharmaceutical Sciences, Iwate Medical University School of Pharmacy, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
  • Uehara Y; Department of Integrated Information for Pharmaceutical Sciences, Iwate Medical University School of Pharmacy, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan.
  • Iwao M; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan. Electronic address: iwao@nagasaki-u.ac.jp.
Bioorg Med Chem ; 25(24): 6563-6580, 2017 12 15.
Article em En | MEDLINE | ID: mdl-29133033
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores de Proteínas Quinases / Receptores ErbB / Compostos Heterocíclicos de 4 ou mais Anéis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores de Proteínas Quinases / Receptores ErbB / Compostos Heterocíclicos de 4 ou mais Anéis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article