Tissue injury of the remnant liver following radiofrequency-assisted partial hepatectomy.
J BUON
; 22(5): 1172-1179, 2017.
Article
em En
| MEDLINE
| ID: mdl-29135099
ABSTRACT
PURPOSE:
To evaluate remnant liver tissue damage in a pig model of radiofrequency (RF)-assisted liver resection employing either the sequential coagulate cut (SCC) Belgrade technique using a monopolar RF electrode or the one using the bipolar Habib-4x device.METHODS:
Sixteen pigs underwent either a) resection of part of the left lateral and left median hepatic lobes employing the SCC (SCC group), the Habib-4X (H group) or the "crushclamp" technique (CC group) or b) sham operation (Sham group). Forty-eight hours later, tissue specimens were excised from the right lateral hepatic lobe for histopathological examination and immunohistochemical assessment of tissue injury, mitosis and inflammation.RESULTS:
Histopathologic lesions, apoptotic activity, HSP 40 and TNFα expression were more intense, while mitotic activity was less prominent in the SCC group technique compared to H group. Comparison between CC and H groups suggested the pivotal role of partial hepatectomy (PH) per se in the changes noted in H group.CONCLUSION:
The Habib-4X liver resection technique proved to be less injurious in the remnant liver tissue after PH compared to the SCC technique.
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Base de dados:
MEDLINE
Assunto principal:
Laparoscopia
/
Hepatectomia
/
Fígado
/
Neoplasias Hepáticas
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article