Effect of Synthetic High Density Lipoproteins Modification with Polyethylene Glycol on Pharmacokinetics and Pharmacodynamics.

Li, Dan; Fawaz, Maria V; Morin, Emily E; Ming, Ran; Sviridov, Denis; Tang, Jie; Ackermann, Rose; Olsen, Karl; Remaley, Alan T; Schwendeman, Anna

Li, Dan; Fawaz, Maria V; Morin, Emily E; Ming, Ran; Sviridov, Denis; Tang, Jie; Ackermann, Rose; Olsen, Karl; Remaley, Alan T; Schwendeman, Anna.

Afiliação

Sviridov D; National Heart, Lung and Blood Institute, National Institutes of Health , Building 10-2C433, 10 Center Drive, MSC 1666, Bethesda, Maryland 20892, United States.
Remaley AT; National Heart, Lung and Blood Institute, National Institutes of Health , Building 10-2C433, 10 Center Drive, MSC 1666, Bethesda, Maryland 20892, United States.

Mol Pharm ; 15(1): 83-96, 2018 01 02.

Article em En | MEDLINE | ID: mdl-29141139

Assuntos

Lipoproteínas HDL/química; Nanopartículas/química; Polietilenoglicóis/química; Apolipoproteína A-I/química; Colesterol/química

Palavras-chave

HDL; PK−PD modeling; apolipoprotein A-I mimetic peptides; apolipoproteins; cholesterol; lipoprotein remodeling; lipoproteins/metabolism; pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Nanopartículas / Lipoproteínas HDL Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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